Paul Harris is a scientist at a small research facility on the outskirts of Boston. After a weekend tryst with Danielle, an attractive co-worker, leaves him wanting more, his unreciprocated desires gradually mold into an acute infatuation over the following months. Paul's suppressed resentments and perverse delusions become unhinged, triggering a horrific course of events that mercilessly engulf a tortured past and fugitive present.